Drug Interactions Of Provigil
Provigil belongs to a class of drugs called. Severe Interactions. Don't drink alcohol while taking Provigil (modafinil). It is not practi- cal to try to memorize the many CYP3A4 substrates, but it would be prudent to be familiar with the most common CYP3A4 inhibitors and inducers since such drugs are likely to interact with approximately half of all drugs on the market..There are 402 drug interactions with Provigil (modafinil) Provigil (modafinil) disease interactions. This is a drug that prevents platelets from sticking to one another Wellbutrin is not a controlled drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Modafinil does not take the place of getting enough sleep. Modafinil (Provigil) and amphetamines are chemically dissimilar Modafinil affects an enzyme that may alter the blood concentration of some drugs such as opioids and some anti-viral medications. NOTE: This is not a comprehensive safety evaluation or complete list of potentially harmful drug interactions Before Using. Drug interaction overview CYP3A4/5 substrates Modafinil moderately induces CYP3A4/5, which may result in lower systemic exposure of CYP3A4/5 substrates (eg, hormonal contraceptives, cyclosporine, midazolam, triazolam). These interactions can increase your risk of side effects, including drowsiness, memory loss, and difficulty breathing Interactions. Introduction Modafinil is a eugeroic drug approved by regulatory agencies in many countries for the treatment of narcolepsy and associated sleep disorders metabolic interaction between modafinil and the substrates of this enzyme (e.g., S-warfarin, phenytoin). It is thought to work by altering the natural chemicals (neurotransmitters) in the brain. Topics A-Z Slideshows Images Quizzes Supplements Medications. The potential for interactions of PROVIGIL with highly protein-bound drugs is considered to be minimal. (See PRECAUTIONS, Drug Interactions, Other Drugs, Warfarin) Blood thinners can also be prescribed after some surgeries, such as hip or knee replacement surgery. Identify these minor or nonsignificant modafinil oral (Provigil Oral) interactions with the RxList drug interaction checker tool. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media. Other medications that may lead to Provigil drug interactions include propranolol, tricyclic antidepressants, and certain protease inhibitors The prescribing information for Modafinil products clearly states there is an interaction with hormonal contraceptives, but provides no information about how this is known. Interactions can make your drugs less effective or cause more side effects. There are 9 disease interactions with modafinil which include: cardiac disease; hypertension; liver disease; bipolar disorders; psychiatric disorders; psychotic disorders; renal dysfunction; seizure disorders; cardiovascular. Provigil (modafinil) is a medication that promotes wakefulness. Consult your healthcare professional (e.g., doctor or pharmacist) for more in. Do not take medications containing modafinil. Your doctor may increase or decrease your. Provigil is a prescription brand-name medication that's most often used drug interactions of provigil to treat excessive sleepiness caused by narcolepsy, sleep apnea, and shift work. But the list also includes some surprises -- household name drugs that shouldn't be taken with ED pills -- including Flomax, Provigil and grapefruit juice. BRAND NAME(S): Provigil.
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Drug Information on Provigil (modafinil) includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. An interaction between modafinil and clozapine has been reported in a case report that resulted in clinical side effects. I'm concerned about a few possibly interactions of other things I take, but mostly with hormonal birth control specifically Praziquantel: (Major) In vitro and drug interactions studies suggest that the CYP3A4 isoenzyme is the major enzyme involved in praziquantel metabolism. Identify these contraindicated and dangerous modafinil oral (Provigil Oral) drug combinations to avoid with the RxList drug interaction checker tool. These interactions can increase or decrease drug levels in your blood, which can reduce the effectiveness of the medicines or increase your risk of side effects. Provigil can decrease the level of estrogen medications in the blood. When taken together with progesterone, they can reduce the desired pharmacologic effects of progesterone. warnings, drug interactions, allergic reactions, or adverse effects. Provigil (modafinil) has many drug interactions and can lower the strength of your birth control pill, so use an additional form of birth control while using Provigil (modafinil). It is also used to help you stay awake during work. Interaction with Alcohol: No known alcohol interaction.. This can be especially important for women taking birth control pills, patches, or rings, as these forms of birth control may be less effective if combined with Provigil.You should use an alternative or backup form drug interactions of provigil of contraception (such as condoms) while taking Provigil and for at least one month after starting the drug Modafinil: This medication is used to treat narcolepsy. Data sources include IBM Watson Micromedex (updated 4 May 2020), Cerner Multum™ (updated 2 June 2020), Wolters Kluwer™ (updated. Provigil (modafinil) drug interactions. There are 9 disease interactions with Provigil (modafinil) which include: cardiac disease; hypertension; liver disease; bipolar disorders; psychiatric disorders; psychotic disorders; renal dysfunction. This document does not contain all possible drug interactions.Keep a list of. Provigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. com' about Provigilit is a stimulant drug to keep you awake among other thingsI make sure that I check drug interactions, side effects whenever I get a new medication, or even just for reminders. geriatric-specific problems are not expected to limit the usefulness of modafinil in the elderly. Moderate Drug-Drug Interaction: cyclobenzaprine (cyclobenzaprine) and modafinil (modafinil) Coadministration with modafinil may decrease the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme.. Other medications that may lead to Provigil drug interactions include propranolol, tricyclic antidepressants, and certain protease inhibitors Medications that may cause negative Provigil drug interactions include warfarin, cyclosporine, and diazepam. Does Provigil Interact with other Medications? These medications are not usually taken together. Some drugs increase plasma. Results presented by Robertson and Hellriegel suggest that clinically significant drug-drug interactions with modafinil are most likely connected to effects on two hepatic enzymes: CYP3A4/5, which is the most prevalent human CYP enzyme, and CYP2C9 metabolic interaction between modafinil and the substrates of this enzyme (e.g., S-warfarin, phenytoin). You might wonder that after taking Modafinil you will test false-positive for another drug, such as an amphetamine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Of these, 209 cause undesired drug interactions. However, in an interaction study in healthy volunteers, chronic modafinil treatment did not show a significant effect on the pharmacokinetics of warfarin when compared to placebo. Introduction Modafinil is a eugeroic drug approved by regulatory agencies in many countries for the treatment of narcolepsy and associated sleep disorders Drug interactions with temazepam can occur if it is combined with alcohol, barbiturates, narcotics, or other sleep medications. This is unlikely. Drug interactions may change how your medications work or increase your risk for serious side effects. Check with your doctor for other drug interactions before taking modafinil. This includes narcolepsy, sleep apnea, and shift work sleep disorder. USES: Modafinil decreases extreme sleepiness due to narcolepsy and other sleep disorders such as difficult/irregular breathing during sleep (e.g., obstructive sleep apnea/hypopnea syndrome-OSAHS). Let your healthcare provider know if you take this drug. Provigil may also be used for purposes not listed in this medication guide Modafinil drug interactions.